For real, though, I really wish I could easily run Office with Bottles or something like that. Never managed to make it work

My use case: I like to have all my emails stored locally just in case some disaster happens with the copies in the cloud; I also get to have both personal and work email addresses, from different providers, in one organized and unified interface, and the same goes for tasks, calendars and contacts; and some features from big web clients are sometimes too nosy for my taste (suggested replies, pushing their calendar, messaging, tasks and contacts products, etc)