What do you love about Kanazawa? Should I visit there?

All the houses where I live are being built by immigrants.

When they added the Borg “queen”, I was really bummed - because I had definitely thought of them as an autonomous collective.

I’m an atheist, but I also pray to a vague “higher power” every morning. My sense is that the prayer helps whether I believe or not.

Captain Picard day? First Contact day?

https://youtu.be/J1DAmmROUX8?si=sepM4PtDn2MsTwqv

Ladies want a man who can sew

I loved using PLUA on the Palm Pilot back in the day

My friend loved these books, but I haven’t read them myself

Got me! I’m a communist and very far from gruntled.

I loved Turbo Pascal so much. Wrote my own DOS windowing system. When the object oriented stuff came out,it was mind blowing but still so accessible.

We will be wanting updates on how that went.

I feel like the zero-covid policy could have worked if they had used an mRNA vaccine and vaccinated the elderly.

Ask the cow what she thinks?

Congratulations!! I love it that you know exactly how many days.

The slightly slower onset of nicotine in the vape (compared to smoking) probably did make it a little easier to quit.

Ants make honey?

star trek.website

Abstract

A hallmark of eukaryotic aging is a loss of epigenetic information, a process that can be reversed. We have previously shown that the ectopic induction of the Yamanaka factors OCT4, SOX2, and KLF4 (OSK) in mammals can restore youthful DNA methylation patterns, transcript profiles, and tissue function, without erasing cellular identity, a process that requires active DNA demethylation. To screen for molecules that reverse cellular aging and rejuvenate human cells without altering the genome, we developed high-throughput cell-based assays that distinguish young from old and senescent cells, including transcription-based aging clocks and a real-time nucleocytoplasmic compartmentalization (NCC) assay. We identify six chemical cocktails, which, in less than a week and without compromising cellular identity, restore a youthful genome-wide transcript profile and reverse transcriptomic age. Thus, rejuvenation by age reversal can be achieved, not only by genetic, but also chemical means.

https://www.aging-us.com/article/204896/text

Do we have ol’ lemmy stuff now?

Can one still download Swype?