Ohh so melatonin leads to adenosine production, which caffeine blocks. so NO SLEEP is the smart bet. that makes a lot of sense, yeah! and when you think about it, coffee at night is gonna make for poor sleep no matter how much melatonin you take.
Ohh so melatonin leads to adenosine production, which caffeine blocks. so NO SLEEP is the smart bet. that makes a lot of sense, yeah! and when you think about it, coffee at night is gonna make for poor sleep no matter how much melatonin you take.
So caffeine binds to adenosine receptors to block adenosine’s drowsiness effect. Melatonin binds to melatonin receptors to regulate circadian rhythms. As far as how adenosine interacts with melatonin, no idea. I’m no biochemist and what I’m about to say could be 100% incorrect, but it seems that adenosine is involved in melatonin production?
So if it’s true that adenosine leads to melatonin production, then I’m guessing that the adenosine-blocking effect of caffeine would be (partially?) negated by ingesting a melatonin supplement, especially in the massive doses that they sell.
My money is on SLEEP.
Mmmm those are good. I like classic tuna. or kimchi! guess where ive eaten them most lol
it’s literally just rice and seaweed with some sesame oil
whoa wait a minute. I didn’t realize which comment i was replying to. I read three different articles and found NOTHING stating she relapsed.
I do similar documentation and I can promise you that “minimal abstinence outside the hospital” does NOT mean relapse.
I’m gonna have to ask to see the citation or ask you to delete your comment for misinfo
‘minimal abstinence outside of hospital.’”
I’m not sure why folks seem to think ‘minimal abstinence outside of hospital’ is a smoking gun. That’s pretty much how medical staff should document an alcoholic whose sobriety only began while hospitalized. It means she hasn’t been able to quit drinking!
When has that happened?
Yes, I read the article three times over, trying to chase down false info someone posted in here. His offer is irrelevant. The prognosis was not good enough for him to donate. They only included it in the article for the melodrama. It’s nothing more than an “I would die for her!” moment. Well, I’m glad the medical board did not condone assisting him with suicide.
Lying about substance use to a confidential healthcare provider is not going to do you any good. If you have drank so much that you are having liver failure, they will know you are lying. If you haven’t drank that much, what’s the purpose of lying? To perpetuate the addiction?
I assume you were not getting a transplant? The risks of regurgitation during surgery is in no way comparable to the risk of relapse in someone with hx alcohol use disorder in early remission. Addiction is a terrible beast. I am sad that she died too, but we have to blame the systems of addiction, not the medical board.
I believe this is FALSE:
[she] relapsed into drinking while on the transplant list,
Where does it say this? I reread it 3 times. That’s a huge part of the story and not one you should just make up!
Giving a donor liver to an alcoholic, who only quit drinking upon diagnosis? Hell no.
Ahh yes the time traveler illusion. Vsauce did a great video on this. Often the styles we wear tell our age more than we realize. An old looking photograph looks old because the subject wears what old people tend to wear. (Among other factors.)
Our generation is just the pink spandex generation I guess?
Oh come on, now you’re just feigning ignorance. The body types correspond to both modes of human sexual dimorphic presentations. Just because you take away the names doesn’t mean the dimorphic traits are absent. It IS a sexually dimorphic character creation system. So within that, let’s look at who gets to be the default and who gets to be the “second sex” (highly recommend reading de Beauvoir, again). OP is taking issue with not just the veiled binary but also the hierarchy within it.
Let me put it this way. Imagine if the body types were no longer sexually dimorphic but had varied skin tones. And despite the fact that we know skin tones present in a variety of ways, they only offered light peach skin tones and dark skin tones. And they made the secondary one the darker skin tone. Maybe you or I would have a problem with it, maybe we wouldn’t. But could you understand why someone might take issue with that? It’s a fair objection to make, whether we can conceive of a solution or not.
And hey I think OP’s solution would apply pretty well here: let us create characters with a variety of presentations! Or maybe just take away the “light” and “dark” options? A lot of people in this thread responded with great rationale from game dev standpoints, and that stuff is valid. I can see why devs do things the way they do. But I can also see why OP doesn’t like it.
depends your native language and regional accent
just leave way earlier for everything and plan to do something to keep you busy when you get there. bring a book, a game, a yo-yo, or go wander around and talk to people and make new friends
I will always upvote whoever posts this stuff. spam me with it!
OOPS sex is a social construct too
Thank you. I’ll do my best regardless. Will you be joining us?