People don’t generally change their gender on a whim, so that doesn’t make the info less useful. (Even if it did, trans people are like 2% of the population, so it would still apply for everyone else.) Men and women have different perspectives and life experiences because the world treats them differently. Do you think knowing the age, race, or country demographics would be pointless, too?
I have the same mutations. In me they caused severe depression for almost 20 years. Started megadosing l-methylfolate, and I wanted to live again practically overnight. So yeah, it can def make you feel different.