Boustrophedon (boost-ruh-FEE-d’n, meaning “as the ox turns”) is a writing style mainly used in a number of ancient civilizations, where the direction of reading changes with each and every line. So, say, the first line you read left-to-right, and then the second line you read right-to-left, and then the third line is left-to-right again, and so on. This way of writing had several benefits for ancient peoples even though nowadays writing backwards every other line sounds crazy to us.
I don’t know how it would actually work to read comic book panels and speech bubbles in a boustrophedon order, so it was really just a dumb joke.
At the same time, advice I’ve heard is to not “turn every social interaction into an interrogation”. People have told me that I ask too many questions and should talk about myself more. So to me the expectation seems to be striking a balance. Sigh.