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Cake day: June 25th, 2023

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  • Yeah I was going to say: who’s this guy?

    Found this after a very quick search: https://www.npd.com/about-npd/industry-experts/mat-piscatella/

    Mat Piscatella’s career has spanned the entertainment software industry, including tenure with Warner Bros and Activision. His industry experience ranges from business planning, analysis, and forecasting to operational and strategic planning. A self-proclaimed “game geek,” Piscatella has worked in the industry for close to 15 years.

    Video game brands he has worked on include Call of Duty, LEGO, Batman: Arkham, Guitar Hero, DreamWorks, Mortal Kombat, and Marvel. Piscatella regularly works with key industry trade associations and is collaborating with colleagues on new initiatives for NPD. He has extensive experience presenting to and advising senior leadership for the video game industry.

    His experience outside of entertainment software include marketing and sales roles for IRI and Banana Boat Suncare. He has an MBA in marketing from San Diego State University, and a BA in political science from California State University, San Bernardino.




  • Long story short: bacteriophage are extremely difficult to fit in the current legal/regulatory framework of the medical/pharma world/system.

    Bacteriophage are not stable compounds such as chemical molecules (antibiotics, etc…). They evolve and change, adapting to bacterial evolution (or just spontaneously because we're talking about organisms, who sometimes just changes). It may be an advantage from a efficacity point of view, buts it's a big no-no from a regulation point of view.

    This makes is harder to have real trials (even if things progress slowly).

    Then you have all the biological questions about injecting live virus in an patient and the risk of immune response.

    Then you have the complexity of both producing phages in a stable manner (remember: these fuckers have a tendcy to "evolve" on their own) as well as shipping them (require refrigeration all the way, contrary to antibiotic pills).

    Source: bacteriophage were the subject of my master thesis, even if it was a while ago.